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Name: Biotin

Synonyms: d- Biotin; Vitamin H

Molecular Formula: C10H16N2O3

Molecular Weight: 244.31

CAS Number: 58-85-5

EINECS: 200-399-3

Character: Biotin is colorless to almost colorless crystalline Powder. Melting point 232 -233℃. Solubility in 25 (mg/100ml):water -22; 95% ethanol -80. Sparingly soluble in acidic or alkaline solution, can not soluble in other conventional organic solvent. Decompose when meet alkali or oxidant.

Applications: Biotin is nutrition extender. It can be used as auxiliary in the processing of food. It can prevent skin disease and improve lipid metabolism. Take too much raw albumen will lead to a biotin shortage.

Specification: USP34

Item

Specification

Identification

To match with the reference IR spectrum

Specific rotation

+89° ~ +93°

Residual solvents (Toluene)

890ppm Max.

Assay

97.5 ~ 100.5%

Lead

2mg/kg Max.

Arsenic

1mg/kg Max.

Cadmium

1mg/kg Max.

Mercury

0.1mg/kg Max.

Mesh size

100% pass 300 mesh

Specification: EP7

Item

Specification

Characters

A white or almost white, crystalline powder

Identification

A.    IR: To match with the reference IR spectrum

B.     TLC: The principal spot in the chromatogram obtained with test solution is similar in position and size to the principal spot in the chromatogram obtained with reference solution

C.    Color reaction: The bromine water is decolorized

Appearance of solution

Clear and colorless

Specific optical rotation

+89° ~ +93°

Related substances

Meets EP requirement

Heavy metals

10ppm Max.

Loss on drying

1.0% Max.

Sulfated ash

0.1% Max.

Assay

98.5 ~ 101.0%

Mesh size

100% pass 300 mesh

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